6-TRIFLUOROMETHYL-1H-INDOLE-2-CARBOXYLIC ACID METHYL ESTER - Names and Identifiers
6-TRIFLUOROMETHYL-1H-INDOLE-2-CARBOXYLIC ACID METHYL ESTER - Physico-chemical Properties
Molecular Formula | C11H8F3NO2
|
Molar Mass | 243.18 |
Melting Point | 169.8-170.8℃ |
Storage Condition | Sealed in dry,Room Temperature |
6-TRIFLUOROMETHYL-1H-INDOLE-2-CARBOXYLIC ACID METHYL ESTER - Risk and Safety
Risk Codes | R36 - Irritating to the eyes
R37/38 - Irritating to respiratory system and skin.
|
Safety Description | S26 - In case of contact with eyes, rinse immediately with plenty of water and seek medical advice.
S36/37/39 - Wear suitable protective clothing, gloves and eye/face protection.
|
HS Code | 29339900 |
6-TRIFLUOROMETHYL-1H-INDOLE-2-CARBOXYLIC ACID METHYL ESTER - Introduction
methyl 6-(trifluoromethyl)-1H-indole-2-carboxylate is an organic compound with the molecular formula C12H9F3NO2 and a molecular weight of 257.20g/mol.
Nature:
-Appearance: Colorless crystalline or powdery solid.
-Melting point: about 82-85°C.
-Boiling point: about 325 ℃.
-Solubility: Soluble in organic solvents such as ethanol, chloroform, dichloromethane, etc.
Use:
- methyl 6-(trifluoromethyl)-1H-indole-2-carboxylate is commonly used as an intermediate in organic synthesis and can be used to synthesize various drugs, pesticides and other organic compounds.
-It can also be used as a synthetic intermediate of plant hormones for the production of hygromycin.
Preparation Method:
methyl 6-(trifluoromethyl)-1H-indole-2-carboxylate is generally prepared by esterification reaction. A common method is to react 3-trifluoromethylbenzoic acid with indole, and then carry out esterification reaction to obtain the target product.
Safety Information:
- methyl 6-(trifluoromethyl)-1H-indole-2-carboxylate is an organic compound that has certain toxicity and needs to be used and stored properly.
-Take appropriate protective measures during operation, such as wearing protective glasses, gloves and lab clothes.
-avoid inhalation, contact with the skin or into the digestive tract, such as accidental contact should be immediately washed with plenty of water.
-During storage, keep a dry and well-ventilated environment, and avoid contact with oxidants and other substances, avoid fire and high temperature.
-If it is necessary to dispose of the waste of this compound, it should be disposed of correctly in accordance with local regulations.
Last Update:2024-04-09 02:00:48